New blood test finds elusive fetal gene problem



































A NEW non-invasive blood test for pregnant women could make it easier to catch abnormalities before their child is born.












Human cells should have two copies of each chromosome but sometimes the division is uneven. Existing tests count the fragments of placental DNA in the mother's blood. If the fragments from one chromosome are unusually abundant, it might be because the fetus has an extra copy of that chromosome. But triploidy, where there are three copies of every chromosome, is missed, since the proportion of fragments from each chromosome is the same.












California-based company Natera uses an algorithm to calculate the most likely genotype for the fetus. To do this it looks at single letter variations called SNPs in the parents and compares this to a database of the most common SNPs patterns in the population. This genotype is then compared with placental DNA.












This approach can catch triploidy since the whole fetal genotype is the reference rather than a single chromosome. The method was presented last week at the Society for Maternal-Fetal Medicine in San Francisco.












This article appeared in print under the headline "No hiding place for fetal gene errors"


















































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German horsemeat scandal traced to Poland






BERLIN: Horsemeat found in beef products withdrawn from German shelves has been traced to a supplier in Poland, news weekly Spiegel reported on Sunday, citing European officials.

Spiegel said that beef products with traces of horse found in goulash sold by low-cost retailer Aldi were produced by German firm Dreistern Konserven, which in turn bought its meat via a dealer from Mipol, a Polish-based firm.

Dreistern Konserven acknowledged in a statement on its website that traces of horse DNA had been discovered in its products but insisted it was merely a processing firm.

"Dreistern is not involved in slaughtering nor the chopping up of meat. It buys meat already chopped up, either fresh or frozen, only from certified meat deliverers," the statement said.

Nearly 50,000 jars of this goulash were delivered to Aldi, said Spiegel, citing information from the European Union's Rapid Alert System for Food and Feed (RASFF).

Spiegel also said another unnamed supplier in northern Poland had delivered some 20 tonnes of meat worth 60,000 euros ($80,000) to German firm Vossko via a Danish dealer.

Vossko supplies Liechtenstein-based firm Hilcona, which in turn supplies German firm Gusto, which manufactured beef tortelloni that was withdrawn from Austrian and German branches of budget food firm Lidl after horsemeat was discovered.

EU authorities are scrambling to reassure consumers after falsely-labelled meat has come to light in several European countries via a sprawling chain of production spanning a maze of abattoirs and suppliers across the continent.

- AFP/fa



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Samsung HomeSync is a Jelly Bean-powered Apple TV rival



Samsung's not content with just making smart TVs, taking another lunge into your living room with HomeSync, an Android-powered media hub.


The glossy black box, announced today at Mobile World Congress in Barcelona, has an HDMI connection, but also hooks up to other gadgets over Wi-Fi or Bluetooth. The HomeSync streams
Android movies, TV shows and games, but Samsung promises the system will also work with Galaxy smart phones, giving smart phone owners the power to beam their home movies or photos onto the big screen.


Samsung says the HomeSync will feature a 'Jelly Bean media player', so while there's no detail yet on the HomeSync's interface, it should be broadly familiar to anyone who's toyed around with Android before. Access to the Google Play store is also confirmed.

You get up to eight separate accounts on one device, so each family member or flat-mate can create their own space on the HomeSync's 1TB hard drive. You can share stored files with another account, or if you're concealing footage you'd rather keep private, there's the option to lock your data down with file encryption and user IDs.


Powering the system is a 1.7GHz dual-core processor, while other hardware niceties include USB 3.0, micro USB and an optical audio connection.


Homesync goes head-to-head with
Apple TV, which is currently a popular choice if you're looking for a box to sit next to your gogglebox and stream movies and TV. HomeSync's appeal will depend greatly on how many movie options there are available, and it'll need a comprehensive selection of flicks if it wants to compete with Apple's own device.


There's no word on pricing yet, but Samsung's touting an April release date. Stay tuned, and let me know if you'd buy this box by dropping a note in the comments.

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Elderly Abandoned at World's Largest Religious Festival


Every 12 years, the northern Indian city of Allahabad plays host to a vast gathering of Hindu pilgrims called the Maha Kumbh Mela. This year, Allahabad is expected to host an estimated 80 million pilgrims between January and March. (See Kumbh Mela: Pictures From the Hindu Holy Festival)

People come to Allahabad to wash away their sins in the sacred River Ganges. For many it's the realization of their life's goal, and they emerge feeling joyful and rejuvenated. But there is also a darker side to the world's largest religious gathering, as some take advantage of the swirling crowds to abandon elderly relatives.

"They wait for this Maha Kumbh because many people are there so nobody will know," said one human rights activist who has helped people in this predicament and who wished to remain anonymous. "Old people have become useless, they don't want to look after them, so they leave them and go."

Anshu Malviya, an Allahabad-based social worker, confirmed that both men and women have been abandoned during the religious event, though it has happened more often to elderly widows. Numbers are hard to come by, since many people genuinely become separated from their groups in the crowd, and those who have been abandoned may not admit it. But Malviya estimates that dozens of people are deliberately abandoned during a Maha Kumbh Mela, at a very rough guess.

To a foreigner, it seems puzzling that these people are not capable of finding their own way home. Malviya smiles. "If you were Indian," he said, "you wouldn't be puzzled. Often they have never left their homes. They are not educated, they don't work. A lot of the time they don't even know which district their village is in."

Once the crowd disperses and the volunteer-run lost-and-found camps that provide temporary respite have packed away their tents, the abandoned elderly may have the option of entering a government-run shelter. Conditions are notoriously bad in these homes, however, and many prefer to remain on the streets, begging. Some gravitate to other holy cities such as Varanasi or Vrindavan where, if they're lucky, they are taken in by temples or charity-funded shelters.

In these cities, they join a much larger population, predominantly women, whose families no longer wish to support them, and who have been brought there because, in the Hindu religion, to die in these holy cities is to achieve moksha or Nirvana. Mohini Giri, a Delhi-based campaigner for women's rights and former chair of India's National Commission for Women, estimates that there are 10,000 such women in Varanasi and 16,000 in Vrindavan.

But even these women are just the tip of the iceberg, says economist Jean Drèze of the University of Allahabad, who has campaigned on social issues in India since 1979. "For one woman who has been explicitly parked in Vrindavan or Varanasi, there are a thousand or ten thousand who are living next door to their sons and are as good as abandoned, literally kept on a starvation diet," he said.

According to the Hindu ideal, a woman should be looked after until the end of her life by her male relatives—with responsibility for her shifting from her father to her husband to her son. But Martha Chen, a lecturer in public policy at Harvard University who published a study of widows in India in 2001, found that the reality was often very different.

Chen's survey of 562 widows of different ages revealed that about half of them were supporting themselves in households that did not include an adult male—either living alone, or with young children or other single women. Many of those who did live with their families reported harassment or even violence.

According to Drèze, the situation hasn't changed since Chen's study, despite the economic growth that has taken place in India, because widows remain vulnerable due to their lack of education and employment. In 2010, the World Bank reported that only 29 percent of the Indian workforce was female. Moreover, despite changes in the law designed to protect women's rights to property, in practice sons predominantly inherit from their parents—leaving women eternally dependent on men. In a country where 37 percent of the population still lives below the poverty line, elderly dependent relatives fall low on many people's lists of priorities.

This bleak picture is all too familiar to Devshran Singh, who oversees the Durga Kund old people's home in Varanasi. People don't pay toward the upkeep of their relatives, he said, and they rarely visit. In one case, a doctor brought an old woman to Durga Kund claiming she had been abandoned. After he had gone, the woman revealed that the doctor was her son. "In modern life," said Singh, "people don't have time for their elderly."

Drèze is currently campaigning for pensions for the elderly, including widows. Giri is working to make more women aware of their rights. And most experts agree that education, which is increasingly accessible to girls in India, will help improve women's plight. "Education is a big force of social change," said Drèze. "There's no doubt about that."


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Las Vegas Strip Shooting Suspect ID'd












Las Vegas police identified a suspect today in a shooting on the strip that caused a Maserati to hit a taxi and burst into flames, killing three people.


Ammar Harris, 26, has been named a suspect in the Thursday skirmish that killed three people, including rapper Kenny Clutch.


The altercation between Harris and Clutch, 27, whose legal name was Kenneth Cherry Jr., is believed to have originated in the valet area of a Las Vegas hotel, police said.


Police said Harris fired several rounds into a Maserati that was being driven by Cherry as both vehicles continued northbound on glitzy Las Vegas Boulevard.


The rapper's expensive sports car careened out of control after he was shot, slamming into several cars, including a taxi. The impact caused the cab to burst into flames, killing the driver, Michael Boldon and a female passenger. Witnesses said it looked like the car exploded.


"He was a number one guy," Carolyn Jean Trimble, Boldon's sister, told ABC News.








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"I looked out my window and I could see one vehicle down here on the corner of the intersection totally engulfed in flames," witness John Lamb told ABC News.


Boldon, 62, and his passenger, who has not yet been identified, were both killed, as was Clutch.


Timble said her brother loved driving his taxi around Vegas.


"He came to live with me in Las Vegas last year to help take care of our mother, and the first day he got here he said, 'I have to get a job.' The second day, I came home from work, and he said he got a job," she recalled.


"He says, 'You'll never guess what it is,' and I said, 'what,' and he said, 'taxi cab driver,' and we both fell out laughing," Trimble said. "He loved that job. He never complained. He'd come home and tell me stories about what happened, who he picked up."


Boldon was a single father who raised a 36-year-old son and was a new grandfather. His grandson was named after him, Trimble said.


"Of all the people to take from this earth," she said. "But I guess the Lord needed him."


A passenger in the Maserati was hit and sustained only a minor injury to his arm. Clutch died at University Medical Center.


His father, Kenneth Cherry Sr., expressed his grief for the loss of his son while speaking with ABC News.


"This is something you never really, really ever want to experience as a parent, to lose a child before you go," he said.


Harris is described as 5-foot-11 and 180 pounds. Anyone with information is asked to contact the Las Vegas Metro Police Department's homicide division.



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Amazon to open market in second-hand MP3s and e-books






















A new market for second-hand digital downloads could let us hold virtual yard sales of our ever-growing piles of intangible possessions






















WHY buy second-hand? For physical goods, the appeal is in the price – you don't mind the creases in a book or rust spots on a car if it's a bargain. Although digital objects never lose their good-as-new lustre, their very nature means there is still uncertainty about whether we actually own them in the first place, making it tricky to set up a second-hand market. Now an Amazon patent for a system to support reselling digital purchases could change that.












Amazon's move comes after last year's European Union ruling that software vendors cannot stop customers from reselling their products. But without technical support, the ruling has had no impact. In Amazon's system, customers will keep their digital purchases – such as e-books or music – in a personal data store in the cloud that only they can access, allowing them to stream or download the content.












This part is like any cloud-based digital locker except that the customer can resell previous purchases by passing the access rights to another person. Once the transaction is complete, the seller will lose access to the content. Any system for reselling an e-book, for example, would have to ensure that it is not duplicated in the transaction. That means deleting any copies the seller may have lying around on hard drives, e-book readers, and other cloud services, since that would violate copyright.












Amazon may be the biggest company to consider a second-hand market, but it is not the first. ReDigi, based in Boston, has been running a resale market for digital goods since 2011. After downloading an app, users can buy a song on ReDigi for as little as 49 cents that would costs 99 cents new on iTunes.












When users want to sell an item, they upload it to ReDigi's servers via a mechanism that ensures no copy is made during the transfer. Software checks that the seller does not retain a copy. Once transferred, the item can be bought and downloaded by another customer. ReDigi is set to launch in Europe in a few months.












Digital items on ReDigi are cheaper because they are one-offs. If your hard drive crashes and you lose your iTunes collection you can download it again. But you can only download an item from ReDigi once – there is no other copy. That is the trade-off that makes a second-hand digital market work: the risk justifies the price. The idea has ruffled a few feathers – last year EMI sued ReDigi for infringement of copyright. A judge denied the claim, but the case continues.


















Used digital goods can also come with added charm. ReDigi tracks the history of the items traded so when you buy something, you can see who has owned it and when. ReDigi's second-hand marketplace has grown into a social network. According to ReDigi founder John Ossenmacher, customers like seeing who has previously listened to a song. "It's got soul like an old guitar," he says. "We've introduced this whole feeling of connectedness."












It could be good for business too if the original vendors, such as iTunes, were to support resale and take a cut of the resell price. Nevertheless, Amazon's move bucks the industry trend. Microsoft's new Xbox, for example, is expected not to work with second-hand games.












But the market could change rapidly now that Amazon's weight is behind this, says Ossenmacher. "The industry is waking up."












This article appeared in print under the headline "Old MP3, one careful owner"




















































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Hockey: Five-a-side format to make debut in S'pore






SINGAPORE: A new format of hockey introduced by the International Hockey Federation is set to make its international debut in Singapore.

The Boys U-16 Asia Cup competition, which will take place in April, will be the first official hockey tournament to use the five-a-side format.

Since October, 15 boys from the Singapore team have been training at the Sengkang Hockey stadium and they are looking forward to competing on a smaller pitch.

National U-16 player Ahmad Faris said: "In five versus five, we are allowed to shoot from anywhere so there are definitely going to be more goal scoring opportunities, we can expect higher scorelines."

For goalkeeper Wee Wei Xuan, the new format will make his job slightly tougher.

"In the 11-a-side format, the goal keeper gets to rest and like walk around but this five-a-side is a lot more challenging which makes it more fun," said Wee.

Ten nations are lining up to do battle at Sengkang in early April and powerhouses like Pakistan will be leading the Asian charge.

The tournament will also function as the Asian qualifiers for next year's Youth Olympic Games.

Only two teams will make the cut but host Singapore remains optimistic due to the new format of play.

National U-16 coach Coen Van Putten said: "It is new for everybody. What we do is we focus on our own performance and we hope we are prepared well. I think we are prepared well but it's always interesting to see what other teams come up with."

Fans are expected to take to the new format too.

The Singapore Hockey Federation is expecting a full-house here at the Sengkang Hockey stadium during the Asia Cup.

A carnival like atmosphere will be created similar to the buzz during the 2009 Junior World Cup and 2010 Youth Olympic Games.

- CNA/fa



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Nokia Lumia 720, 520 photos leak ahead of MWC



Nokia Lumia 720 leak

This could be the Nokia Lumia 720 you're gazing at.



(Credit:
EVLeaks)


BARCELONA, Spain--Days before Nokia has a chance to unveil its Mobile World Congress lineup, apparent leaks of its two upcoming smartphones, the Lumia 720 and Lumia 520, have already surfaced to go along with some bubbled-up specs.



If the images, provided by EvLeaks, prove accurate, the mid-tier Lumia 720 and more entry level 520 will feature the same bright colors and signature look as other smartphones in Nokia's Lumia line.


Expect to see handsets in cyan, yellow, red, white, and black.


According to rumored specs, the Lumia 720 will feature a 4.3-inch display with Nokia's ClearBlack glare-reducing filter, plus a 1GHz dual-core processor. The Windows Phone 8 device could also sport a 6-megapixel camera, 2-megapixel front-facing shooter, 8GB of storage, and a microSD card slot.


Meanwhile, the lower-end 520 might deliver a 4-inch touch screen and 5-megapixel, and no front-facing camera, but keep the 720's other specs, including 512MB RAM.



Nokia Lumia 520 leaked images

Nokia is expected to announce the Lumia 520 this week.



(Credit:
EVLeaks)


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Space Pictures This Week: Space Rose, Ghostly Horses








































































































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Great Energy Challenge Blog













































































































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Cyberattacks Bring Attention to Security Reform











Recent accusations of a large-scale cyber crime effort by the Chinese government left many wondering what immediate steps the president and Congress are taking to prevent these attacks from happening again.


On Wednesday, the White House released the administration's Strategy on Mitigating the Theft of U.S. Trade Secrets as a follow-up to the president's executive order. The strategy did not outwardly mention China, but it implied U.S. government awareness of the problem.


"We are taking a whole of government approach to stop the theft of trade secrets by foreign competitors or foreign governments by any means -- cyber or otherwise," U.S. Intellectual Property Enforcement Coordinator Victoria Espinel said in a White House statement.


As of now, the administration's strategy is the first direct step in addressing cybersecurity, but in order for change to happen Congress needs to be involved. So far, the Cyber Intelligence Sharing and Protection Act (CISPA) is the most notable Congressional legislation addressing the problem, despite its past controversy.


Last April, CISPA was introduced by House Intelligence Committee Chairman Mike Rogers, R-Mich., and Rep. Dutch Ruppersberger, D-Md. The act would allow private companies with consumer information to voluntarily share those details with the NSA and the DOD in order to combat cyber attacks.






Peter Parks/AFP/Getty Images







The companies would be protected from any liabilities if the information was somehow mishandled. This portion of the act sounded alarm bells for CISPA's opponents, like the ACLU, which worried that this provision would incentivize companies to share individuals' information with disregard.


CISPA passed in the House of Representatives, despite a veto threat from the White House stemming from similar privacy concerns. The bill then died in the Senate.


This year, CISPA was reintroduced the day after the State of the Union address during which the president declared an executive order targeting similar security concerns from a government standpoint.


In contrast to CISPA, the executive order would be initiated on the end of the government, and federal agencies would share relevant information regarding threats with private industries, rather than asking businesses to supply data details. All information shared by the government would be unclassified.


At the core of both the executive order and CISPA, U.S. businesses and the government would be encouraged to work together to combat cyber threats. However, each option would clearly take a different route to collaboration. The difference seems minimal, but has been the subject of legislative debates between the president and Congress for almost a year, until now.


"My response to the president's executive order is very positive," Ruppersberger told ABC News. "[The president] brought up how important information sharing is [and] by addressing critical infrastructure, he took care of another hurdle that we do not have to deal with."


Addressing privacy roadblocks, CISPA backers said the sharing of private customer information with the government, as long as personal details are stripped, is not unprecedented.


"Think of what we do with HIPAA in the medical professions; [doctors do not need to know] the individual person, just the symptoms to diagnose a disease," Michigan Gov. John Engler testified at a House Intelligence Committee hearing in an attempt to put the problem into context.






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